LEADERSHIP TEAM

Kurt Graves

Chairman, President and CEO

Mr. Graves has been Chairman, President and CEO of Intarcia since April 2012, having previously served solely as Chairman of the company since August 2010 and as Acting CEO since October 2011. He is a global industry leader with more than twenty years of U.S. and global general management experience in top-tier U.S. and European based pharmaceutical and biotech companies. He has successfully built and managed several of the largest multi-billion dollar franchises in the industry and developed and launched more than 10 blockbuster brands in a broad range of general medicine, specialty and orphan disease areas. In addition to driving dynamic top and bottom-line growth in large global pharmaceutical companies, Mr. Graves also played a key leadership role in building two highly successful early stage companies; at Astra Merck Pharmaceuticals and Vertex Pharmaceuticals. Prior to joining Intarcia, Mr. Graves was EVP, Chief Commercial Officer and Head of Corporate and Strategic Development at Vertex Pharmaceuticals from 2007 through the end of 2009. Prior to his tenure at Vertex, he spent nearly ten years at Novartis Pharmaceuticals, most recently as Global Head of the General Medicines Business & Chief Marketing Officer for the Pharmaceuticals division. Prior to Novartis, Mr. Graves held several commercial and general management positions at Merck and Astra Merck/Astra Pharmaceuticals where he spent most of his time leading the GI Business Unit responsible for Prilosec and Nexium. In addition to Intarcia, Mr. Graves serves as Chairman of the Board of Radius therapeutics and as a Director at Springleaf Therapeutics and Pulmatrix Pharmaceuticals. Mr. Graves earned his B.S. in Biology from Hillsdale College and has attended numerous executive leadership programs at Harvard, Wharton School of Management and University of Michigan.


James Ahlers

Vice President, Finance and Operations
Chief Financial Officer

Mr. Ahlers joined Intarcia Therapeutics in March 2000. Mr. Ahlers has served as a financial consultant to public and private biotechnology companies including Cytokinetics, GeneSoft and Tularik. He has extensive experience financing and building the infrastructure of growing pharmaceutical and biotechnology companies. In this capacity, Mr. Ahlers has served as the Director of Finance and Administration and managed the initial public offerings of Ansan Pharmaceuticals and Titan Pharmaceuticals. Previously, he was a member of the audit department in the San Francisco office of Deloitte & Touche and manager of Financial Planning and Analysis at Medco Behavioral Care Corporation. Mr. Ahlers earned a B.S. degree from the University of San Francisco in accounting.


Thomas Alessi, Ph.D.

Vice President, Development and Manufacturing

Dr. Alessi joined Intarcia in December 1997 as Executive Director, Regulatory Affairs and Drug Development and was promoted to Vice President, Development in February 2002 with responsibility for the areas of product development, project management, chemistry and manufacturing. Prior to joining Intarcia, Dr. Alessi served as the Senior Director, Regulatory Affairs, Quality Assurance and Project Management at Ansan Pharmaceuticals where he was responsible for successful IND filings and for managing five drug development programs with oversight of vendors for preclinical and clinical studies and manufacturing clinical supplies. Before joining Ansan, Dr. Alessi was Director of Regulatory Affairs and Quality Assurance at Glycomed, Inc. where his duties included oversight and compliance of clinical manufacturing. His previous experience includes regulatory affairs and drug discovery experience in large pharmaceutical companies. Dr. Alessi was Senior Manager of Regulatory Affairs for Schering-Plough working in the Anti-infectives, Allergy Products and Chemisty, Manufacturing, & Controls groups. While at Schering-Plough, Dr. Alessi had regulatory responsibilities for approval and launch of interferon alfa-2b for hepatitis C as well as for hepatitis B. In his CMC role, he served on separate committees for process development and production of solid oral dosage forms, inhaled products, creams and semisolid products and sterile dosage forms, in addition to regulatory review of the CMC sections of Schering-Plough INDs and NDAs. Prior to joining Schering-Plough, Dr. Alessi invented and patented several new families of antidiabetic drugs while working as a Senior Scientist in the drug discovery group at Wyeth-Ayerst. Dr. Alessi earned a B.S. degree at Allegheny College and an M.S. and a Ph.D. in organic synthetic chemistry from the University of Rochester.


Michelle Baron, M.D., FACE

Vice President, Clinical Research
Chief Medical Officer

Dr. Baron joined Intarcia in March 2012 as Vice President, Clinical Research and Chief Medical Officer. Dr. Baron is recognized throughout the industry as an accomplished physician in clinical drug development and medical affairs with deep expertise in cardiovascular, endocrinology and metabolic diseases. Prior to joining Intarcia, Dr. Baron was Vice President, Diabetes U.S. at sanofi-aventis, where her responsibilities included the design and commercialization of a U.S. Diabetes Patient Solutions platform and the assessment of business development opportunities and strategic partnerships for the U.S. Diabetes Division. Prior to that, Dr. Baron spent ten years at Novartis, ending her tenure there as Senior Medical Director, Diabetes Section of the Cardiovascular and Metabolism U.S. Clinical Development and Medical Affairs group. There, she led the team responsible for the planning, execution, monitoring and safe conduct of phase 2-4 diabetes and cardiovascular clinical trials and was a core member of the team designing and executing the clinical development, registration and commercialization strategies for Galvus® (vildagliptin) for the treatment of type 2 diabetes. She previously served as Program Director of the Endocrinology and Metabolism Fellowship Program, the Director of the Osteoporosis Diagnostic Center, and Fellow at the SUNY Health Science Center at Brooklyn, and as an Attending Physician in the Department of Medicine at Kings County Medical Center. She continues to serve as an Assistant Professor in the Department of Medicine's Division of Endocrinology and Metabolism at SUNY. She received her M.D. from Howard University College of Medicine, her B.A. from The Johns Hopkins University and did her postgraduate training in Internal Medicine at Emory University. She is a Fellow of the American College of Endocrinologists, a Diplomate of the American Board of Endocrinology and Metabolism, and a Diplomate of the American Board of Internal Medicine.


David Franklin

Vice President, Commercial Operations

Mr. Franklin joined Intarcia in March 2006 as Vice President, Commercial Operations. Prior to joining Intarcia, Mr. Franklin was Senior Vice President, US Business Unit and Acting Senior Vice President, Global Marketing for Idenix Pharmaceuticals. As head of the US Business from March 2005 through March 2006, Mr. Franklin developed and executed plans for the commercialization of telbivudine, an antiviral for the treatment of chronic hepatitis B, and built the US Business Unit, an organization comprising approximately 40 Medical, Marketing and Sales personnel. From June 2003 until March 2005, Mr. Franklin served as Vice President, Commercial Operations, leading the Idenix Global Marketing group, directing brand development for telbivudine and for a phase II hepatitis C drug candidate and leading commercial efforts to form a global co-promotion and licensing alliance with Novartis AG. Prior to these responsibilities, Mr. Franklin held positions of increasing responsibility with Idenix as Executive Director, Marketing and Corporate Communications and Director, Marketing and played key roles in multiple private and public financing transactions and in business development and licensing transactions. Prior to joining Idenix in 1998, Mr. Franklin was Senior Product Manager, HIV Products for Bristol-Myers Squibb Co. with responsibility for Zerit and Videx, two antiviral therapies for the treatment of HIV infection. Prior to joining the HIV Products Division, Mr. Franklin held sales and sales administration positions within the Bristol-Myers Squibb Oncology Division from 1990 to 1995, responsible for sales force support, incentive compensation and alliance management. Mr. Franklin received a BA from Gettysburg College in 1988.


Owen Hughes, Jr.

Chief Business Officer and Head of Corporate Development

Mr. Hughes joined Intarcia in February 2013 as Chief Business Officer and Head of Corporate Development. Prior to Intarcia, Mr. Hughes served as Director at Brookside Capital, a multi-billion dollar hedge fund that falls under the Bain Capital umbrella. There, he co-managed all public and private healthcare investments including biotechnology, med-tech, and services. Prior to his tenure at Brookside, Mr. Hughes was Senior Portfolio Manager at Pyramis Global Advisors, a Fidelity Investments Company, a Co-founder and Partner at Triathlon Fund Management, an Investment Associate at Ziff Brothers Investments, an Assistant Vice President at Merrill Lynch/Morgan Stanley, where he provided sell-side coverage of specialty healthcare distributors, and a Financial Analyst in the healthcare group at PaineWebber. Mr. Hughes received his B.A. from Dartmouth College, where he received All-Ivy Honors, Academic All-Ivy Honors and was a four-year Letterman on the Varsity Ice Hockey team.


Raymond T. Keane, Esq.

Vice President, General Counsel, and Chief Legal Officer

Mr. Keane joined Intarcia in September 2013 as Vice President, General Counsel, and Chief Legal Officer. Prior to joining Intarcia, he served as Senior Vice President, General Counsel, Secretary, and Chief Compliance Officer of ARIAD Pharmaceuticals through its transition from a research and development platform to a fully integrated global commercial organization.  At ARIAD, he built and led the global commercial legal team to support the company’s first product approval and launch, and created the corporate structure for European operations. He previously spent 20 years at Bristol-Myers Squibb Company (BMS), initially in corporate litigation and quickly moved to the Worldwide Medicines Group, where he had lead legal responsibility for the US marketing approval and launch of a number of blockbuster drugs in the cardiovascular, oncology and virology therapeutic areas, including Plavix®, Avapro®, Erbitux® and Reyataz®. Ultimately, as the senior lawyer for the Global Marketing and Strategic Development franchise, he and his team supported the global commercialization of three additional drugs/biologics, providing legal oversight for global marketing strategy, launch campaigns, corporate communications, healthcare professional interactions, and worldwide strategic development. Before joining BMS, Mr. Keane was a trial lawyer associated with two major New York City law firms. He received his B.A. in Economics from Fordham College and his J.D. from Fordham University School of Law.


Jay Smith

Head of Customer Experience & Outcomes (CXO)

Mr. Smith joined Intarcia in December of 2013 as Head of Customer Experience & Outcomes (CXO). It is a new position overseeing a bold new business goal to outperform and redefine industry standards in customer experience optimization. As CXO, Mr. Smith is Intarcia's resident authority and champion fully dedicated to efforts to optimize the positive customer experiences and outcomes with our brands; ITCA 650 and other platform related projects we intend to develop and commercialize. He is 100 percent dedicated to the proactive optimization and continuous improvement of customer experiences with our target patients, providers and payers. With more than 24 years of industry experience in positions of rapidly increasing responsibility, Mr. Smith is eminently qualified for this challenging assignment, having demonstrated world-class success at the senior-most levels of Sales and Marketing at J&J, Novartis and Sunovion (formerly Sepracor). Most recently he served as President at "1-800-DOCTORS," a consumer, patient and physician centric company focused on leveraging technology, including secure digital-video and telephonic platforms, to create the best patient-physician experience possible. In addition to his B.A. in Biology from Westmar College, Mr. Smith successfully completed several executive courses at Harvard, including the 32-week Program for Leadership Development. Outside of work he is extremely versatile in sports, including: an Ironman Triathlete four times, earned a second-degree Black Belt, a former USPT Tennis Professional, and currently a coach of various youth teams. Mr. Smith is married and lives with three teenaged children in Massachusetts.


 

Our Strategy

At Intarcia, our goal is to develop and commercialize drug therapies that deliver an improved therapeutic outcome while enhancing patients' quality of life.


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